Overview

Ketamine Anesthesia in Electroconvulsive Therapy

Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
0
Participant gender:
All
Summary
Does the use of ketamine as the anesthetic medication in electroconvulsive therapy (ECT) accelerate the antidepressant effect of ECT? The study hypothesis was that depressed subjects receiving ECT with ketamine as the anesthetic agent would demonstrate a faster rate of improvement, defined as lower depression ratings after the second ECT than depressed patients receiving ECT with the usual anesthetic agent.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Mayo Clinic
Treatments:
Anesthetics
Ketamine
Methohexital
Criteria
Inclusion criteria:

- Diagnosis of depression, either unipolar or bipolar

- Subjects receiving ECT at the Mayo Clinic

Exclusion criteria:

- Subjects not giving their own consent to ECT

- Subjects with schizophrenia, schizoaffective disorder, or dementia

- Subjects diagnosed with a major neurological disorder such as epilepsy, Parkinson
disease, multiple sclerosis, or a neurodegenerative dementia.