Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children

• Status: Terminated
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the effectiveness of a needle-free jet-injection system with 1% buffered lidocaine for local anesthesia for lumbar punctures compared to a topical anesthetic agent. Our hypothesis is: A needle-free jet-injection system (J-Tip) with 1% lidocaine will provide local anesthesia that is comparable to that of a topical anesthetic agent (EMLA cream) when performing lumbar punctures in children.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Colorado, Denver
• Collaborator: Colorado Clinical & Translational Sciences Institute
• Treatments: EMLA; Lidocaine; Lidocaine, Prilocaine Drug Combination; Prilocaine

Criteria

Inclusion Criteria:

• age ≤4 months or 4-18 years

• ability to report VAS for patients 4-18 years

• require lumbar puncture as part of their clinical care

Exclusion Criteria:

• ages 5-47 months

• developmental delay or inability to complete VAS in older patients

• allergy to lidocaine

• requirement of sedation for procedure

• pre-procedural analgesia treatment except for nonsteroidal anti-inflammatory drugs and acetaminophen.