Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast Cancer
Status:
Terminated
Trial end date:
2011-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as ixabepilone, work in different ways to stop
the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Hydroxychloroquine may help ixabepilone work better by making tumor cells more sensitive to
the drug.
PURPOSE: This phase I/II trial is studying the side effects and best dose of ixabepilone
given together with hydroxychloroquine and to see how well they work in treating patients
with metastatic breast cancer.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Medicine and Dentistry of New Jersey