Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy
Status:
Completed
Trial end date:
2019-07-01
Target enrollment:
Participant gender:
Summary
Randomized clinical trial in the Logo health zone, in Ituri province, Democratic Republic of
Congo to compare seizure freedom in onchocerciasis infested epilepsy patients who ivermectin
treatment once a year compared to 2 and 3 times a year. All participants also receive
anti-epileptic drugs according to local guidelines for epilepsy treatment. Participants will
be followed for 12 months. The primary endpoint is seizure freedom defined as no seizures
during the last fourth months of the trial.