Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular Tachycardia

• Status: Terminated
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether intravenous amiodarone has less cardiac significant adverse events compared to intravenous procainamide in the acute treatment of haemodynamically well tolerated wide QRS tachycardia, the majority of them of probably ventricular origen.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital General Universitario Gregorio Marañon
• Treatments: Amiodarone; Procainamide

Criteria

Inclusion Criteria:

• Patients with stable tachycardia ≥120 lpm, QRS ≥120 ms and haemodynamically well tolerated defined as: 1)Systolic blood pressure ≥90 mmHg, 2) absence of dyspnea at rest, 3)absence of peripheric hypoperfusion signs and 4)no severe angina.

• Age > 18 years

• Written inform consent obtained

Exclusion Criteria:

• Treatment with iv amiodarone or iv procainamide during the previous 24 hours

• QRS tachycardia <120 ms

• Patients with QRS ≥120 ms tachycardia with haemodynamic compromise that requires urgent cardioversion for termination

• Irregular tachycardia

• Tachycardia that is considered as supraventricular due to physician criteria (adenosine and/or vagal manoeuvres response)

• Patient that do not want to cooperate