Overview

Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

Status:
Recruiting
Trial end date:
2028-02-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to assess the safety and efficacy of once daily itacitinib oral administration in participants with diffuse large B-cell lymphoma (DLBCL) who will receive CAR-T cell therapy with axicabtagene ciloleucel (axi-cel).
Phase:
Phase 2
Details
Lead Sponsor:
H. Lee Moffitt Cancer Center and Research Institute
Collaborator:
Incyte Corporation