Isonicotinic Acid Hydrazide Pretreatment With Misoprostol Induction of Abortion in First-trimester Missed Miscarriage

• Status: Not yet recruiting
• Trial end date: 2021-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

This study compares the success rate of Adjuvant isonicotinic acid hydrazide and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy among women with one or more previous cesarean deliveries.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aswan University Hospital
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Gestational age less than 70 days gestation (<10 wks).

• Hemoglobin >10 g/dL.

• BMI between 18.5 kg/m2 and 30 kg/m2.

• Missed abortion

• previous one or more cesarean deliveries

Exclusion Criteria:

• Molar pregnancy

• Fibroid uterus.

• Uterine anomalies.

• Coagulopathy

• Medical disorder that contraindicate induction of abortion (e.g. heart failure).

• Previous attempts for induction of abortion in the current pregnancy.

• Allergy to misoprostol or INH.