The purpose of this study is to test whether the islet cell transplantation procedures and
results from a previous study in Edmonton, Canada, can be repeated. The study also is
designed to learn more about diabetes control using islet cell transplantation.
This is a Phase I/II study (a study that examines effectiveness and looks for side effects).
The transplanting of islet cells has been studied in Type 1 diabetic patients whose blood
sugar levels will not stay normal, despite intensive insulin therapy. A recent study
conducted in Edmonton, Canada, was able to demonstrate that islet transplantation led to
insulin independence in a majority of the patients treated. This study extends the results
obtained from the Edmonton study, which used islet transplantation in Type 1 diabetic
patients with steroid-free immunosuppression.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)