Is Involucrin Has a Role in Verruca Vulgaris? A Clinical and Immunohistochemical Study
Status:
Completed
Trial end date:
2019-10-01
Target enrollment:
Participant gender:
Summary
Vitamin D3 plays important role in keratinocyte differentiation and had been used recently in
verruca vulgaris. Aim of the work: To assess the expression of involucrin in verrucae
vulgaris before and after injection of vitamin D3. Subjects and Methods: This study included
60 patients with verrucae vulgaris subjected to intralesional injection of vitamin D3 at
three weeks interval for a maximum of five sessions. Immunohistochemical assessment of
involucrin was done before and after injection and compared to skin biopsies from 30 healthy
individuals