Iron Supplementation of Marginally Low Birth Weight Infants
Status:
Completed
Trial end date:
2014-11-01
Target enrollment:
Participant gender:
Summary
Iron is essential for brain development and there is a well established association between
iron deficiency in infants and poor neurological development. In Sweden, about 5% of newborns
have low birth weight (< 2500 g). Due to small iron stores at birth and rapid postnatal
growth, they have increased risk of iron deficiency and it is therefore important to prevent
iron deficiency in this population. However, excessive iron supplementation can have adverse
effects in infants such as growth impairment. In a randomized, controlled trial, we are
investigating the effects of 0, 1 or 2 mg/kg/d of iron on brain myelination, cognitive
development and growth in low birth weight infants.
Phase:
Phase 4
Details
Lead Sponsor:
Umeå University
Collaborators:
Jerring Foundation, Sweden Oskar Foundation The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS)