Iron Supplementation in Upper Non-variceal Gastrointestinal Bleeding
Status:
Not yet recruiting
Trial end date:
2026-02-01
Target enrollment:
Participant gender:
Summary
Anemia is a frequent complication of gastrointestinal bleeding, affecting 61% of the
patients. Currently, anemia caused by gastrointestinal bleeding can be treated with iron
supplementation. However, the dose and route of the administration are still a question. The
FIERCE clinical trial aims to compare the effect of intravenous iron supplementation and oral
iron replacement on mortality, unplanned emergency visits, and hospital readmissions in
multimorbid patients with acute nonvariceal gastrointestinal bleeding.