Iron Stores and Skeletal Muscle Metabolism in Chronic Heart Failure
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Iron deficiency may contribute to exercise intolerance by altering mitochondrial oxidative
capacity in skeletal muscle. Functional iron deficiency is common in heart failure patients,
but the relationship to exercise intolerance and mitochondrial oxidative capacity is unknown.
This is a pilot study to determine the feasibility of the use of specialized 31P-MRS and MRI
techniques for measurement of skeletal muscle bioenergetics in patients with heart failure
with and without functional iron deficiency.
Phase:
Phase 1
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health