Overview

Iron Repletion in Chronic Cough and Iron Deficiency

Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
0
Participant gender:
Female
Summary
Chronic cough is more frequent and severe in women than in men. Women often have decreased iron stores, due to menses and pregnancies. Aim of the study: to investigate if iron deficiency has a role in chronic cough by favouring airway hypersensitivity to inhaled irritants.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Turin, Italy
Collaborator:
Regione Piemonte
Treatments:
Histamine
Iron
Loratadine
Omeprazole
Proton Pump Inhibitors
Criteria
Inclusion Criteria:

- Unexplained cough : no detectable trigger for chronic cough identified, such as
persistent rhinitis, chronic sinusitis, gastroesophageal reflux disease and asthma.

- no benefit by prior treatment with antiH1-histaminic drug and proton pump inhibitor.

- iron deficiency.

- normal lung function tests and chest radiography no relevant systemic disease.

- no acute respiratory infection in the last eight weeks.

- no pharmacological treatment in the last two weeks.

Exclusion Criteria: