Overview

Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain Metastases

Status:
Completed

Trial end date:
2014-01-01

Target enrollment:

Participant gender:

Summary

RATIONALE: Drugs used in chemotherapy, such as irinotecan and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects of giving irinotecan together with temozolomide and to see how well it works in treating patients with breast cancer who have received previous treatment for brain metastases.

Phase:

Phase 2

Details

Lead Sponsor:

University of California, San Francisco

Collaborator:

National Cancer Institute (NCI)

Treatments:

Camptothecin
Dacarbazine
Irinotecan
Temozolomide