Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase I
Status:
Terminated
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to find the highest tolerable dose of
lenalidomide combined with Camptosar (irinotecan) as well as to see if this drug combination
can help control malignant gliomas.
Researchers will also study if a special magnetic resonance imaging (MRI) technique (dynamic
MRI scan) is useful in looking at the effect of treatment on the tumor. Another goal is to
learn the effect of lenalidomide on tumor tissue in patients who need surgery for the
disease.