Overview

Irinotecan, 5-Fluorouracil, and Leucovorin in Colorectal Carcinoma

Status:
Completed
Trial end date:
2004-04-01
Target enrollment:
Participant gender:
Summary
This study will examine an investigational (experimental) agent Tetrathiomolybdate (TM) combined with the chemotherapy drugs Irinotecan, 5-Fluorouracil (5-FU) and Leucovorin (LV). This study will evaluate the safety and tolerability of the combination of these drugs when they are used in the treatment of metastatic colorectal cancer. This is a pilot clinical trial which will be studying the reactions of the patient's body and tumor to the experimental treatment described above. The purpose of this study is to find out what kind of side effects this experimental treatment causes and see how often these side effects occur.
Phase:
Phase 2
Details
Lead Sponsor:
University of Michigan Cancer Center
University of Michigan Rogel Cancer Center
Treatments:
Camptothecin
Fluorouracil
Irinotecan
Leucovorin
Molybdenum
Tetrathiomolybdate