Iontophoresis of Treprostinil to Enhance Wound Healing in Diabetic Foot Skin Ulcers
Status:
Recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
Assess the effect of iontophoresis of treprostinil on wound closure over 12 weeks, in
patients with DFU.
In the present study the investigators aim at establishing the proof-of-concept of
iontophoresis of treprostinil as a potential treatment of diabetic foot ulcers in humans. The
main hypothesis is that in patients with DFUs, the pharmacodynamic effect of a PGI2 analogue
potentiates the effect of low-intensity current on microvascular function, tissue oxygenation
and healing.