Investigation of the Influence of Gender on Cardiovascular Function
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
Inflammation is a key initiating and damaging factor in many illnesses including infection,
arthritis and cancer but also of particular relevance to this study in diseases of the heart
and blood vessels (i.e. cardiovascular disease). Much evidence now exists demonstrating that
male sex increases ones risk of cardiovascular disease. More recent evidence demonstrates
that inflammatory responses in females appear to dampened in comparison to age matched males.
Since inflammation is thought to be a key initiating phenomenon in many cardiovascular
disease states the investigators will examine the differences in acute inflammatory responses
between the sexes in healthy volunteers and the impact this has on the function of blood
vessels.