Overview

Investigation of the Efficacy of Acamprosate and Calcium in Comparison to Placebo as Validation of a Behavioural Test for Alcohol Dependence

Status:
Recruiting

Trial end date:
2023-02-28

Target enrollment:

Participant gender:

Summary

Validation of a Test System to develop new medications for alcoholism (TEMA) The 'TEMA', a progressive-work alcohol self-administration paradigm, can be validated by reproducing the effect of Acamprosate and prove the effect of Calcium to reduce motivation to work for alcohol after 14 - 19 days of treatment during a period of 15 - 20 days of alcohol abstinence in a randomized, double-blind, placebo-controlled three-arm parallel-group design.

Phase:

Phase 3

Details

Lead Sponsor:

Technische Universität Dresden

Treatments:

Acamprosate
Calcium
Calcium Carbonate
Calcium, Dietary
Citric Acid