Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's

• Status: Recruiting
• Trial end date: 2027-02-15
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to compare key clinical outcomes of collagenase clostridium histolyticum injections versus surgery for the management of Peyronie's Disease.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Charitable Union for the Research and Education of Peyronie's Disease
• Collaborator: Endo Pharmaceuticals

Criteria

Inclusion Criteria:

• Men with PD

• >18 years old

• Curvature ≥30 degrees

• Ability to achieve an erection satisfactory for intercourse with or without PDE5 inhibitors

Exclusion Criteria:

• Prior treatment with CCH or surgery

• Moderate (shadowing) or severe (>1 cm) penile calcification

• Any contraindications to CCH, PTT, or surgery - as determined by the PI