Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass

• Status: Completed
• Trial end date: 2005-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to see if the heart-lung machine involved in cardiac surgery increases the movement of activated white blood cells from the bloodstream into the patient's tissues and also to see if aprotinin usage during surgery reduces this effect.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Imperial College London
• Collaborator: British Heart Foundation
• Treatments: Aprotinin

Criteria

Inclusion Criteria:

• Primary elective coronary artery bypass surgery

Exclusion Criteria:

• Emergent, urgent or re-do surgery

• Patients on oral corticosteroid medication

• Patients on aspirin therapy < 7 days prior to operation