Investigation of Female Reproductive Hormone Dynamics During Adolescence
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
Irregular menstrual cycles are common in girls for several years after their first menstrual
period. The cause of abnormal menstrual cycles during this time is not well-understood. The
purpose of this study is to: 1) monitor girls during a menstrual cycle (with blood and urine
sampling and serial pelvic ultrasounds) to identify those girls who do not ovulate (release
of an egg from the ovary), and 2) determine whether cycles can be corrected by treating girls
with a short course of low-dose estrogen and progesterone.