Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder Cancer
Status:
Active, not recruiting
Trial end date:
2020-09-01
Target enrollment:
Participant gender:
Summary
Patients diagnosed with low risk non-muscle invasive bladder cancer (NMIBC) are at risk of
frequent low grade recurrence, which usually necessitates surgical intervention under general
anaesthetic. This multicentre study aims to establish the short term efficacy of
chemoresection using chemotherapy within the bladder for the treatment of NMIBC.
Should the levels of complete response following chemoresection meet predefined criteria, a
larger phase III trial would be developed to assess longer term disease related endpoints,
with the aim of standardising management of recurrent low risk NMIBC and potentially removing
the need for over a thousand patients each year to undergo surgery.
Phase:
Phase 2
Details
Lead Sponsor:
Institute of Cancer Research, United Kingdom
Collaborator:
National Institute for Health Research, United Kingdom