Overview Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite Status: Completed Trial end date: 2019-03-29 Target enrollment: Participant gender: Summary This study is investigate the influence of severe hepatic impairment on the pharmacokinetics of acalabrutinib and its metabolite. Phase: Phase 1 Details Lead Sponsor: Acerta Pharma BVCollaborator: AstraZenecaTreatments: Acalabrutinib