Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg

• Status: Recruiting
• Trial end date: 2022-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine the proportion of excellent tracheal intubation conditions at 60 seconds after administration of either rocuronium 1.0 mg/kg or suxamethonium 1 mg/kg in patients with age ≥ 80 years during rapid sequence induction.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Matias Vested
• Treatments: Rocuronium; Succinylcholine

Criteria

Inclusion Criteria:

• Age ≥ 80

• Scheduled for surgery under general anesthesia with indication for rapid sequence induction

• American Society of Anesthesiologists physical status classification (ASA) I to IV

• Informed consent (see appendix 1)

• Body mass index (BMI) < 35 kg/m2

• Read and understand Danish

Exclusion Criteria:

• Neuromuscular disease

• Known allergy to rocuronium and/or suxamethonium

• Known hyperkalemia > 5 mM

• Previous malignant hyperthermia

• Known homozygote plasmacholinesterase gene mutation variant a or s