Intravitreal Pegaptanib in Treatment of Choroidal Neovascularisation Secondary to Pathologic Myopia

• Status: Withdrawn
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Intravitreal pegaptanib for treatment of choroidal neovascularisation secondary to pathologic myopia

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: L.V. Prasad Eye Institute
• Collaborator: Pfizer

Criteria

Inclusion Criteria:

1. Should be willing to participate in the trial.

2. Age less than 55 years.

3. Best corrected visual acuity (BCVA) score of at least 5 letters (20/200), as assessed by ETDRS chart.

4. Myopia of ≥ 6 Diopters.

5. Fluorescein angiographic documentation of CNV.

Exclusion Criteria:

1. Ocular causes, or other ocular disorders leading to vision loss.

2. Maculopathy not related to pathologic myopia.

3. Pregnancy, lactation.

4. Not willing to provide an informed consent.

5. History of previous macular laser including PDT.

6. Other forms of therapy including intravitreal injections.

7. History of intraocular surgery in the past 3 months.

8. Anticipated cataract surgery in the next 6 months.

9. Any active infection or inflammation in the eye.

10. Cases where good quality imaging is not possible, either due to hazy media or extremely high myopia.

11. Patients with uncontrolled glaucoma, with IOP > 21mm Hg on 2 or more medications.

12. Patients with subfoveal scar or significant subretinal haemorrhage occupying more than 50% of lesion size.

13. Eyes with previous retinal detachment.