Overview

Intravitreal Aflibercept for Retinal Non-Perfusion in Proliferative Diabetic Retinopathy

Status:
Completed
Trial end date:
2019-05-01
Target enrollment:
Participant gender:
Summary
The RECOVERY trial will assess the safety and tolerability of 2 mg intravitreal aflibercept injections (IAI) given monthly (Q4WK) or every 12 weeks (Q12WK) for the treatment of retinal capillary non-perfusion (RNP) associated with proliferative diabetic retinopathy (PDR). - Assess the safety and tolerability of IAI for the treatment of proliferative diabetic retinopathy by evaluating the incidence and severity of ocular and systemic adverse events through week 52 - Change in area of retinal capillary non-perfusion, as assessed by central reading center, from baseline through week 52
Phase:
Phase 2
Details
Lead Sponsor:
Charles C Wykoff, PhD, MD
Collaborator:
Regeneron Pharmaceuticals
Treatments:
Aflibercept