Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful Titration
Status:
Completed
Trial end date:
2020-11-21
Target enrollment:
Participant gender:
Summary
Pain is one of the most common and fear symptoms for cancer patients, which seriously affects
the quality of life in cancer patients. At present, oral opioid is the most common route to
administrate cancer pain. However, the patients do not satisfy the pain administration with
oral opioid after successful titration in many cases, especially the cases with severe cancer
pain. Patient controlled analgesia (PCA) with hydromorphone can take analgesic effect
rapidly. The aim of this trial is to compare the maintenance with hydromorphone PCA
intravenously or switch to Sustained-Release Morphine orally after successful titraton with
hydromorphone PCA intravenously in severe cancer pain.