Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management.
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
Local anesthetics (LA) are increasingly used for postoperative pain management.
Speicifically, several studies have found benefit of LA injected intra-abdominally following
abdominal hysterectomy. However, it remains unclear whether the pain relief seen is due to
local anesthetic mechanisms within the abdominal cavity or through systemic absorption. The
aim of this study is to assess whether lidocaine administered intravenously has similar
analgesic efficacy as the same dose administered intra-abdominally in patients undergoing
abdominal hysterectomy. All patients would have rescue analgesia using the patient controlled
analgesia (PCA) pump with morphine in order to achieve adequate pain management during 24 h.