Overview

Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders

Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
By chance the investigators found that iv. silibinin has a potent antiviral effect against the hepatitis C virus. Based on the results of the dose finding study (published) te optima dosing schedule is explored.This study will be evaluate whether the highest active dose given for the optimal time combined with standard of care will result in a sustained virologic response (=cure of hepatitis C).
Phase:
Phase 2
Details
Lead Sponsor:
Medical University of Vienna
Treatments:
Antiviral Agents
Interferons
Peginterferon alfa-2a
Ribavirin
Silybin
Silymarin