Intravenous Nalbuphine Versus Intravenous Dexmedetomidine for Conscious Sedation in Patients Undergoing Colonoscopy

• Status: Not yet recruiting
• Trial end date: 2024-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to compare the sedative, analgesic effect and hemodynamic changes due to dexmedetomidine and nalbuphine during elective colonoscopy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Dexmedetomidine; Nalbuphine

Criteria

Inclusion Criteria:

1. The subject is scheduled for elective colonoscopy.

2. The subject is ≥ 18 years and ≤ 80 years.

3. Both sexes.

4. No obvious abnormalities in preoperative ECG, blood routine ,electrolytes, and other tests .

5. ASA class 1-3.

Exclusion Criteria:

1. Subject is known or believed to be pregnant or lactating women.

2. Patients allergic to α2-adrenergic agonist or sulfa drugs

3. Chronic Opioid Use (daily or almost daily use of opioids for > 3 months).

4. Patients that are immunologically compromised, or receiving chronic steroids (>30 days), excluding inhalers.

5. Sleep apnea syndrome or difficult airway.

6. Patient known to be asthmatic or recent chest infection.

7. Patients that are prisoners.

8. Patient refusal.