Intravenous Lignocaine Infusion in Laparoscopic Donor Nephrectomy
Status:
Recruiting
Trial end date:
2021-07-31
Target enrollment:
Participant gender:
Summary
Background:
Administration of morphine as boluses or via a patient controlled analgesic device (PCA) has
been the standard practice for donors after nephrectomy.
However, administration of morphine is far from being ideal analgesic as it does not provide
optimal dynamic pain relief after major surgery, consistently demonstrate little effect on
surgical stress response and organ dysfunction with high incidences of postoperative
nausea/vomiting, respiratory depression and sedation. Several studies demonstrated
perioperative intravenous lignocaine infusion can improve post-operative pain scores and
morphine consumption in abdominal surgery.
The aim of this study is to identify the effectiveness of intra-operative lignocaine infusion
in lowering postoperative pain and reduce postoperative morphine consumption in patients who
undergo laparoscopic donor nephrectomy.