Intravenous Lidocaine to Supress of Cough Reflex During Anesthesia Emergence
Status:
Unknown status
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
Introduction: Although inflating tracheal cuff using lidocaine is effective for cough
suppression, it may pressure tracheal cuff too much. Intravenous continuous infusion of
lidocaine has emerged recently for most general anesthesia in the context of opioid-sparing
anesthesia for cancer, but the 95% effective dose (ED95) for cough suppression during
anesthesia emergence is not determined yet. Objective: the objectives of this study are to
determine the ED95 of continuous infusion lidocaine for suppressing cough reflex during
extubation by sex and age group.