Intravenous Lidocaine Versus Morphine for Severe Pain in the ED

• Status: Completed
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Objective: Evaluate the analgesic efficacy of intravenous (IV) lidocaine versus provider chosen dose of IV morphine for the treatment of severe pain in the emergency department.

Study design: Open-label, randomized controlled pilot study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alameda Health System
• Treatments: Lidocaine; Morphine

Criteria

Inclusion Criteria:

• Subject has severe pain (NRS ≥7)

• Subject has anticipated ED stay of ≥1 hour

Exclusion Criteria:

• High acuity trauma patients

• Patients deemed to critically ill by ED provider

• Active psychosis

• Pregnancy

• History of heart block or bradycardia

• Allergy to lidocaine or amide type local anesthetic

• History of seizures