Intravenous Iron Sucrose in Arthroplasty

• Status: Unknown status
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of the present study is to determine the impact of intraoperative IV-iron supplementation on postoperative oxygenation profile by comparing the postoperative PaO2/FiO2 ratio with or without IV-iron supplementation in old patients undergoing elective uni-limb arthroplasty surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Konkuk University Medical Center
• Treatments: Ferric Compounds; Ferric Oxide, Saccharated; Iron

Criteria

Inclusion Criteria:

• Patients with osteoarthritis in knee joint undergoing elective uni-limb total knee arthroplasty surgery

• Patients provided a written informed consent.

• Patients with s-ferritin < 300 mg/dl (male) or 200 mg/dl (female)

• Patients with preoperative serum hemoglobin concentration >13 g/dL (male) and >12 g/dL (female)

• Patients with PaO2/FiO2 ratio >150

Exclusion Criteria:

• Patients with history of anaphylaxis, iron overload, active infection.

• Patients with endocrine disease

• Patients received or receiving intraoperative and preoperative blood salvaged, allogenic blood transfusion, anti-fibrinolytic agents or recombinant human erythropoietin, or undergoing acute normovolemic hemodilution.