Intravenous Ibuprofen for Laparoscopic Bariatric Surgery
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
Primary objective of this study is to test hypothesis that IV ibuprofen decreases 24 hours
morphine requirement using IV PCA in patients after laparoscopic bariatric surgery. Secondary
objective is to determine if it decreases respiratory depression measured using RD, improves
area under curve (AUC) for pain scores at rest (AUCr) and with cough (AUCa) and pressure pain
threshold (PPT) (important for mobilization). Tertiary objective is to compare incidence of
nausea/vomiting, sedation, itching, blood transfusion, over sedation, urinary retention, GI
or surgical bleeding, renal dysfunction, time to clears and baseline activity in ibuprofen
and control groups.