Intravenous (IV) Pantoprazole for Gastroesophageal Reflux Disease (GERD) in Neonates and Infants
Status:
Completed
Trial end date:
2012-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine how the body uses and eliminates pantoprazole, a
drug used to treat GERD. This is a pharmacokinetic (PK) study. PK is a measure of how much
drug is in the blood and how long it takes to leave the body. It is hypothesized that younger
infants will need a lower dose than older children to achieve the same PK measurement.
The results of this study will be used to determine the best dose of the drug to use in each
age group. Pantoprazole is a drug used to decrease acid production. The use of pantoprazole
has not been approved for use in children. Pantoprazole is approved for use of acid-related
and stomach disorders in adults.