Intravenous Fluids in Hospitalised Children

• Status: Completed
• Trial end date: 2019-04-15
• Target enrollment: 0
• Participant gender: All

Summary

The main objective of the trial is to evaluate the risk of hypokalemia following administration of a isotonic solution compared to a hypotonic solution in acutely ill hospitalised children, who need intravenous fluid therapy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Oulu
• Collaborator: Oulu University Hospital
• Treatments: Pharmaceutical Solutions; Plasma-lyte 148

Criteria

Inclusion Criteria:

• Acutely ill hospitalised children

• Need for intravenous fluid therapy

Exclusion Criteria:

• An initial plasma sodium concentration of lower than 130 mmol/L

• An initial plasma sodium concentration of higher than 150 mmol/L

• An initial plasma potassium concentration of lower than 3.0 mmol/L

• Need for 10% glucose solution

• Diabetes

• Diabetes insipidus

• Diabetic ketoacidosis

• Renal disease that needs dialysis

• Protocol-determined chemotherapy hydration

• Severe liver disease

• Inborn errors of metabolism that need protocol-determined fluid therapy