Migraine headache has a 1-year period prevalence in the US of 11.7% and accounts for
approximately 1.2 million migraine visits to US emergency departments per year . There are
numerous studies that discuss treatment for migraine and other benign headaches within the
emergency department (ED), however, there are very few that discuss specifically the use of
intravenous fluids (IVF) for headache treatment. Many of these studies look at various
options for treating migraine and other benign headaches: treatment options include dopamine
antagonists, opioids, non-steroid anti-inflammatory drugs (NSAIDs), triptans, anti-epileptics
and ergot derivatives. Comparisons have been done between many of these treatment options
with dopamine antagonists appearing to be the most effective, compared to other treatments
The dopamine antagonist with the most evidence and availability for benign headaches is
prochlorperazine. Given that IVF administration is a common part of treatment regimen for
benign headache patients in the emergency department and given the lack of randomized trials
in adults, the investigators aim to study the use of IVF on pain reduction in headache
patients in the adult ED. There has been one randomized trial in pediatrics that shows IVF
may help in patients with migraines, whereas the adult literature has no randomized control
trials and a review of data shows that fluids do not help relieve pain in migraine headache
patients. This study will include both adult and pediatric patients presenting to the
Emergency Department with complaint of benign headache.