Intravenous Clonidine for Sedation in Infants and Children Who Are Mechanically Ventilated - Dosing Finding Study
Status:
Completed
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
Critically ill infants and children who are mechanically ventilated are often given large
doses of opiates and benzodiazepines to provide analgesia-sedation. These drugs significantly
cause tolerance and dependence, depresses the drive to breathe, and thus prolongs the need
for mechanical ventilation and the associated complications. We propose IV CLON could be used
as effectively as DEX.