Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency Department

• Status: Unknown status
• Trial end date: 2018-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates intravenous (IV) buprenorphine versus IV morphine for the management of severe, acute pain among emergency department (ED) patients. ED patients with severe pain will be randomized in equal proportion to receive IV buprenorphine or IV morphine.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alameda Health System
• Treatments: Buprenorphine; Morphine

Criteria

Inclusion Criteria:

• ED patients with acute pain NRS ≥7 warranting IV opioid analgesia (according to ED provider)

Exclusion Criteria:

• Patient refusal

• pregnancy

• level 1 trauma patients

• patients deemed critically ill by provider

• patients in custody

• patients on methadone

• Patients who have received or taken any short acting opioid medication in the past 12 hours.

• Patients who have received or taken any long acting opioid medication in the past 24 hours.