Overview

Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells

Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
0
Participant gender:
Female
Summary
Intrauterine injection of hCG around the time of implantation may increase endometrial Treg cells and improve implantation. It has been demonstrated that regulatory T cells expand during pregnancy. hCG was found to be secreted by the embryo immediately after fertilization and has chemoattractant properties to Treg cells.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
The Egyptian IVF-ET Center
Treatments:
Chorionic Gonadotropin
Criteria
Inclusion Criteria:

- Male factor infertility

- Ovulatory factor infertility

- Unexplained infertility

- Female age less than 39

Exclusion Criteria:

- Azoospermia

- Tubal factor infertility

- Pelvic endometriosis