Intratendinous Genipin Injection in Horses With Tendon Injuries

• Status: Completed
• Trial end date: 2023-01-04
• Target enrollment: 0
• Participant gender: All

Summary

Our study is the first to use genipin, a naturally occurring collagen cross-linking agent, as a therapeutic agent to treat superficial digital flexor tendon (SDFT) injuries in horses. The promising approach of intratendinous genipin injection and tendon mechanical enhancement could be a viable alternative to current therapies for SDFT injuries.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Zurich
• Treatments: Genipin

Criteria

Inclusion Criteria:

• clinical and sonographic evidence of a tendon injury

Exclusion Criteria:

• in the final analysis, only superficial digital flexor tendon injuries were included

• if follow-up was less than 12 m due to euthanasia, death or other reasons, horses were excluded from the study