Overview

Intraperitoneal Local Anesthetic in Bariatric Surgery Study (iLABS Study)

Status:
Completed
Trial end date:
2018-04-27
Target enrollment:
0
Participant gender:
All
Summary
Obesity is a metabolic disorder that has gradually become a prevalent public health problem and is becoming one of the leading causes of death and disability worldwide. The most efficacious therapy for morbid obesity today is bariatric surgery. Bariatric surgery increases life expectancy by correcting the comorbidities associated with obesity, improves the quality of life, and is associated with reduced morbidity and mortality. There is an increase application of laparoscopic procedures as it is considered to cause less pain than traditional open surgery, smaller incision, reduced blood loss and shorter postoperative stay, which cuts down on hospital cost. However, postoperative pain still exists causing unpleasant experience for the patient and at times causes a delayed discharge. Pain after bariatric surgery is a result of many mechanisms such as tissue injury, abdominal distention, local trauma of the stomach, chemical irritation of the peritoneum, and the pneumoperitoneum and this pain potentially can prolong hospital stay and lead to increased morbidity, and bariatric surgeons are striving to minimize the morbidity of current procedures to improve patient outcomes and this gave rise to the use of intraperitoneal local anesthetics (LA). It was found that the use of intraperitoneal LA in laparoscopic cholecystectomy is safe, and it results in a statistically significant reduction in early postoperative abdominal pain. Many studies were done to evaluate the efficacy of intraperitoneal LA in laparoscopic cholecystectomy, gynecologic procedures and appendectomy but to date there are limited studies done to evaluate the role of intraperitoneal LA in bariatric surgery. The aim of this study is to evaluate the effectiveness of intraperitoneal instillation of local ropivacaine on postoperative abdominal pain after laparoscopic sleeve gastrectomy (LSG). We hypothesized that the administration of intraperitoneal instillation of local ropivacaine would help reduce postoperative pain.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Dr. Tikfu Gee
Treatments:
Anesthetics
Anesthetics, Local
Ropivacaine
Criteria
Inclusion Criteria:

i. Patients age 18 years and above ii. Patients who can communicate in English or Malay
iii. Patients undergoing elective laparoscopic sleeve gastrectomy iv. Able to give informed
consent

Exclusion Criteria:

i. Patients age below 18 years ii. Patients are allergic to ropivacaine or local
anaesthetic iii. Inability to informed consent iv. American Society of Anesthesiologists
Classification > 3 v. Patients with chronic medical diseases (eg. Ischaemic heart disease,
cardiac arrhythmias, cardiac failure) and chronic opioid treatment vi. Patients with
previous foregut surgery including esophageal, gastric, liver, and pancreas resections