Intraperitoneal Local Anesthetic in Bariatric Surgery Study (iLABS Study)
Status:
Completed
Trial end date:
2018-04-27
Target enrollment:
Participant gender:
Summary
Obesity is a metabolic disorder that has gradually become a prevalent public health problem
and is becoming one of the leading causes of death and disability worldwide. The most
efficacious therapy for morbid obesity today is bariatric surgery. Bariatric surgery
increases life expectancy by correcting the comorbidities associated with obesity, improves
the quality of life, and is associated with reduced morbidity and mortality. There is an
increase application of laparoscopic procedures as it is considered to cause less pain than
traditional open surgery, smaller incision, reduced blood loss and shorter postoperative
stay, which cuts down on hospital cost. However, postoperative pain still exists causing
unpleasant experience for the patient and at times causes a delayed discharge. Pain after
bariatric surgery is a result of many mechanisms such as tissue injury, abdominal distention,
local trauma of the stomach, chemical irritation of the peritoneum, and the pneumoperitoneum
and this pain potentially can prolong hospital stay and lead to increased morbidity, and
bariatric surgeons are striving to minimize the morbidity of current procedures to improve
patient outcomes and this gave rise to the use of intraperitoneal local anesthetics (LA). It
was found that the use of intraperitoneal LA in laparoscopic cholecystectomy is safe, and it
results in a statistically significant reduction in early postoperative abdominal pain. Many
studies were done to evaluate the efficacy of intraperitoneal LA in laparoscopic
cholecystectomy, gynecologic procedures and appendectomy but to date there are limited
studies done to evaluate the role of intraperitoneal LA in bariatric surgery. The aim of this
study is to evaluate the effectiveness of intraperitoneal instillation of local ropivacaine
on postoperative abdominal pain after laparoscopic sleeve gastrectomy (LSG). We hypothesized
that the administration of intraperitoneal instillation of local ropivacaine would help
reduce postoperative pain.