Intraorbital Injection Versus Oral Steroid in Anterior Idiopathic Orbital Inflammation

• Status: Recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

A multicenter randomised double-arm clinical trial, to compare safety and efficacy of oral versus intralesional injection of steroid in a group of patients suffering from idiopathic orbital inflammation is designed. Outcome measures include number of recurrences, duration of remission, and side effects.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Iran University of Medical Sciences
• Collaborators: Mashhad University of Medical Sciences; Shahid Beheshti University of Medical Sciences; Tehran University of Medical Sciences
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate; Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• Dacryoadenitis based on clinical findings and/or imaging with and without adjacent recti muscle myositis

Exclusion Criteria:

• Abnormal thyroid-stimulating hormone

• Systemic Vasculitides

• Bilateral Orbital Inflammation

• Collagen Vascular Diseases

• One Seeing Eye

• Glaucoma

• Diabetes Mellitus