Intraoperative Ultrasonic Atomization of Lidocaine and Postoperative Pulmonary Complications
Status:
NOT_YET_RECRUITING
Trial end date:
2025-12-30
Target enrollment:
Participant gender:
Summary
There is high incidence of postoperative pulmonary complications (PPCs) in patients undergoing major abdominal surgeries.PPCs significantly prolongs the hospital stay of patients, increases their economic burden, and raises the mortality rates within 30 days and 1 year after surgery. The inflammatory response during the perioperative period plays an important role in the occurrence and development of PPCs. The anti-inflammatory effect of lidocaine has a potential lung protection mechanism. The purpose of this study is to explore the effect of ultrasonic atomization of lidocaine on the incidence of PPCs. The investigators hypothesized that intraoperative ultrasonic atomization of lidocaine could reduce the incidence of PPCs.