Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
Status:
Terminated
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether, for surgery of the tibia, one dose of
methadone provides better control of pain afterward as compared to morphine, which is the
usual drug given to control pain after surgery. Immediately after the beginning of general
anesthesia ("intraoperatively"), subjects will receive one dose of either methadone or
morphine, in the amount of 0.2 milligrams per kilogram of body weight, intravenously.
The primary hypothesis is that, subjects who receive one dose of methadone intraoperatively
will require less pain medicine than subjects who receive one dose of morphine
intraoperatively.