Intraoperative Magnesium Sulfate Administration During Orthotopic Liver Transplantation

• Status: Recruiting
• Trial end date: 2021-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of study is to assess the effect of intraoperative use of magnesium sulfate in liver donating patients in reducing post-operative morphine requirements in early postoperative 24 hour in adult living liver donor.The authors hypothesize that magnesium sulfate can be used to efficiently reduce postoperative morphine consumption in the early 24 hours postoperatively as evident in other surgery types.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Fayoum University Hospital
• Treatments: Magnesium Sulfate; Morphine

Criteria

Inclusion Criteria:

• Age (18-50).

• American Society of Anesthesiology (ASA) physical state I or II.

• Normal serum electrolytes.

Exclusion Criteria:

• Impaired hepatic or renal functions.

• Various degree of heart block.

• Hypertension

• Diabetes

• Myopathy or any neurological disorder.

• History of long term opioid use

• Patients treated with calcium channel blockers

• Patients with known allergy to drug used.

• Pregnant woman

• Obesity (Body Mass Index > 30).