Intraoperative Clonidine for Postoperative Pain Management in Patients Undergoing Surgical Treatment for Endometriosis

• Status: Recruiting
• Trial end date: 2024-08-31
• Target enrollment: 0
• Participant gender: Female

Summary

The role of a single dose of intraoperative clonidine on postoperative opioid requirements, pain intensity and opioid-related side effects in patients undergoing surgical treatment for endometriosis remains scarcely explored. A prospective double-blind, randomised controlled trial investigating the effect of a single-dose of intraoperative clonidine in patients undergoing surgical treatment for endometriosis is therefore conducted.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Aarhus
• Collaborator: Aarhus University Hospital
• Treatments: Clonidine

Criteria

Inclusion Criteria:

• Patients scheduled for surgical laparoscopic treatment of endometriosis at Aarhus University Hospital

Exclusion Criteria:

• Age < 18 years

• American Society of Anesthesiologists (ASA) physical status IV or V

• Allergy to clonidine

• Inability to provide informed consent

• Known severe renal insufficiency

• Known severe bradyarrhythmia

• Pregnancy, lactation:

• Daily opioid consumption the last 7 days before surgery

• Pain intensity >5 on more than half of the days during the last month