The duration of the effect of autonomic neural blockade (ANB) is the most critical limitation
for successful clinical application. The analgesic effect using only 0.5% bupivacaine may
wear off after 12 to 18 hours. We have prolonged this effect using a combination of
bupivacaine and dexamethasone. In this protocol, we aim to study three different local
anesthetic combinations to prolong the effect of the ANB.
Phase:
Phase 3
Details
Lead Sponsor:
Universidad Simón Bolívar
Treatments:
Anesthetics Anesthetics, Local BB 1101 Bupivacaine Clonidine Dexamethasone Dexamethasone acetate